Publications

This survey study examines which dietary modifications or supplements were perceived as beneficial for pain management by individuals with endometriosis.

This study examines how psychological stress during pregnancy influences biological markers of gut permeability and inflammation, and how these effects may differ between women with and without irritable bowel syndrome (IBS). We assessed stress, anxiety, and depression levels alongside circulating biomarkers in pregnant women at mid-gestation. Findings revealed that heightened stress and mood disturbances were linked to inflammatory and metabolic changes, suggesting a measurable biological signature of prenatal stress. These results highlight potential pathways through which maternal stress may affect both gut health and fetal development, underscoring the importance of targeted stress-reduction interventions during pregnancy.

Pregnancy is a transformative period marked by profound physical and emotional changes, with far-reaching consequences for both mother and child. Emerging research has illustrated the pivotal role of a mother’s diet during pregnancy in influencing the prenatal gut microbiome and subsequently shaping the neurodevelopment of her offspring.

Understanding the interrelationship between the gut microbiota and host physiology, although still in its relative infancy, has taken important steps forward over the past decade. In the context of brain disorders including those characterized by neurodevelopmental and neurodegenerative changes there have been important advances.

This study explores the link between gut microbiota composition and persistent post-surgical pain (PPSP) in women undergoing breast cancer surgery. Nearly half of participants reported ongoing pain 12 weeks after surgery, and those with higher pain levels showed lower gut microbial diversity. Certain bacterial species were associated with the presence or absence of pain, suggesting the gut microbiome may influence recovery and the development of chronic post-surgical pain.

Many parts of the animal and human body host groups of bacteria, viruses, and fungi that together are known as the microbiome. Microbiomes do not cause disease but are important for the healthy working of many systems in the body, including for reproduction and fertility.

Melatonin is a pineal indolamine, allegedly known as a circadian rhythm regulator, and an antioxidative and immunomodulatory molecule. In both experimental and clinical trials, melatonin has been shown to have positive effects in various pathologies, as a modulator of important biochemical pathways including inflammation, oxidative stress, cell injury, apoptosis, and energy metabolism.

This study explores why women tend to experience pain more often and more intensely than men. This paper investigates how the gut microbiome, the community of bacteria in our digestive system might influence how people feel and respond to pain. The study also examines how factors such as sex, menstrual cycle, and hormonal contraceptive use could help explain differences in pain sensitivity between men and women.

Endometriosis is a neuroinflammatory reproductive disorder defined by the presence of endometrial-like tissue (lesions) outside the uterus that is difficult to diagnose and treat. Given the high prevalence of pain, fatigue, and gastrointestinal symptoms among patients, the research explores which dietary modifications and supplements are perceived as beneficial for symptom relief. Insights from this work may help clarify the potential role of nutritional and microbiome-targeted interventions in managing endometriosis-associated pain.